VitaminK7®: New Perspectives for Fermented Vitamin K2 as MK7

 

VITAMK7®, MK7 AS FERMENTED VITAMIN K2 – NEW PERSPECTIVES

These days, Vitamin K2, known as menaquinone-7 (MK7), is one of the most attractive ingredients for human health, and according to the market's new GIR (Global Information Research) study; it is expected to grow approximately 24.7% CAGR over the next five years. In this direction, the market, which was USD 73 million in 2019, is expected to reach USD 270 million in 2024. The importance of Vitamin K2 in human health is increasing day by day, and people are becoming more aware. As new significant roles are being revealed, various clinical studies demonstrate that Vitamin K2 plays an important role in bone and heart health. Vitamin K2 in menaquinone-7 (MK7) form is a key player in calcium utilization, helping to build strong bones and prevent arterial calcification. MK7 was first isolated from natto, a traditional Japanese food, and is obtained from bean fermentation with Bacillus subtilis natto bacteria. Natto food has a consumption history dating back 1,000 years. Gnosis by Lesaffre; under the vitaMK7® brand, is today the leader in Vitamin K2 obtained through fermentation of B. subtilis natto. With production continuing for over 10 years, it is the only European producer of Vitamin K2, known as MK7, without intermediaries or brokers. The production process is conducted in its own approved cGMP facility in compliance with ISO and HACCP quality systems, which are the strictest quality standards. The entire supply chain is continuously monitored and operated with complete transparency: Gnosis by Lesaffre ensures its customers how pure, stable, safe and high-quality Vitamin K2 is as MK7 and provides the opportunity to control every step of the production process of VitaMK7® products for understanding the implementations. Furthermore, VitaMK7® also has KOSHER and HALAL certificates. VitaMK7® offers the "Clean label" advantage, which is a globally recognized market value. It is obtained from biofermentation of a natural microbial strain, grown under strict control, and highly purified. In VitaMK7®'s patented fermentation production, Bacillus subtilis natto, which occurs naturally in the environment during the production of Japanese natto foods, is used. The pure profile was obtained with very high content of all-trans active isomer (more than 99%) and without synthetic chemicals. Thanks to this clean profile, VitaMK7® reduces cross-reactions with other ingredients and provides higher efficacy and stability to formulations.

New Application Trend

The most promising and developing sector for Vitamin K2, known as MK7, is fortified milk and dairy products applications. Although milk does not contain MK7, the fats contained in it are ideal food matrices and carriers for lipophilic vitamins like MK7. Dairy products have lipid compositions ranging from 1-2% fat-free milk to 9% fat concentrated yogurt. Fortified milk is widely used globally to help people obtain nutrients that may be lacking in their diets. Vitamin D, Vitamin A, Vitamin B9 (folate), minerals and micronutrients can be cited as examples. Findings published in the latest Nutrafoods Journal show comparisons of serum vitamin K levels in healthy individuals. Here, 1 mg of Gnosis by Lesaffre vitaMK7® in powder form or pre-emulsified dispersion was diluted in 1% fat milk, and the resulting product was given as a single oral dose. Although both formulations increased serum MK7 levels in all subjects, the results clearly demonstrate the difference MK7 makes, with the emulsified vitamin formula creating a significant increase in bioavailability over 8 hours. For bone health, enrichment of dairy products with MK7 is completed with an easy-to-use and high-bioavailability (Ca++, Vit. D and Vit. K2) "perfect blend." For information, you can visit the websites of Gnosis by Lesaffre and vitaMK7®. You can contact us at the Arısan Grup booth at the Food & Nutritional Ingredients Fair, Hall 9, Booth 860. Dr. Lorena Carboni - Scientific Advisor - Gnosis